Books/Book Chapters

Linear Algebra for Multivariate Signal Processing and Machine Learning (in Japanese)
K. Sekihara
Kyoritu Shuppan, 2019.

Bayesian Signal Processing (in Japanese)
K. Sekihara
Kyoritu Shuppan, 2015.

Electromagnetic Brain Imaging: A Bayesian Perspective
K. Sekihara and S. S. Nagarajan
Springer Verlag, 2015

Statistical Signal Processing (in Japanese)
K. Sekihara
Kyoritu Shuppan, 2011.

Imaging the electrical neuronal generators of EEG/MEG

R. D. Pascual-Marqui, K. Sekihara D. Brandeis and C. M. Michel
Electrical Neuroimaging, edited by C. M. Michel et al.,
Cambridge University Press, 2009, Pages:49-77

Adaptive Spatial Filters for Electromagnetic Brain Imaging
K. Sekihara and S. S. Nagarajan
Springer Verlag, 2008

Neuromagnetic Source Reconstruction and Inverse Modeling
K. Sekihara and S. S. Nagarajan
Modeling and Imaging of Bioelectric Activity - Principles and Applications, edited by B. He,
Kluwer Academic/Plenum Publishers, 2004, Pages:213-250

Neuromagnetic inverse modeling: applications of eigenstructure-based approaches to extracting cortical activities from MEG data
K. Sekihara and D. Poeppel and A. Marantz and Y. Miyashita
Image, Language, Brain, edited by A. Marantz et. al,
The MIT Press, 2000, Pages: 197-231

Journal papers (2019 - 1992)


Comparison of DSSP and tSSS algorithms for removing artifacts from vagus nerve stimulators in magnetoencephalography data.
Cai C, Kang H, Kirsch HE, Mizuiri D, Chen J, Bhutada A, Sekihara K, Nagarajan SS
J Neural Eng. 2019 Nov 12;16(6):066045. doi: 10.1088/1741-2552/ab4065.
PDF

Robust Empirical Bayesian Reconstruction of Distributed Sources for Electromagnetic Brain Imaging.
Cai C, Diwakar M, Chen D, Sekihara K, Nagarajan SS
IEEE Trans Med Imaging. 2019 Jul 31. doi: 10.1109/TMI.2019.2932290. [Epub ahead of print]
PDF

Noninvasive Mapping of Premature Ventricular Contractions by Merging Magnetocardiography and Computed Tomography.
Satoshi Aita, Kuniomi Ogata, Kentaro Yoshida, Takeshi Inaba, Hisanori Kosuge, Takeshi Machino, Yasuaki Tsumagari, Ai Hattori, Yoko Ito, Yuki Komatsu, Kensuke Sekihara, Hitoshi Horigome, Kazutaka Aonuma, Akihiko Nogami, Akihiko Kandori and Masaki Ieda.
JACC: Clinical Electrophysiology DOI: 10.1016/j.jacep.2019.06.010
PDF

Evaluation of a dual signal subspace projection algorithm in magnetoencephalographic recordings from patients with intractable epilepsy and vagus nerve stimulators.
Cai C, Xu J, Velmurugan J, Knowlton R, Sekihara K, Nagarajan SS, Kirsch H.
Neuroimage. 2018 Nov 28. pii: S1053-8119(18)32103-7. doi: 10.1016/j.neuroimage.2018.11.025.
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Visualization of the electrical activity of the cauda equina using a magnetospinography system in healthy subjects.
Ushio S, Hoshino Y, Kawabata S, Adachi Y, Sekihara K, Sumiya S, Ukegawa D, Sakaki K, Watanabe T, Hasegawa Y, Okawa A.
Clin Neurophysiol. 2018 Nov 12;130(1):1-11. doi: 10.1016/j.clinph.2018.11.001.
PDF

Hierarchical multiscale Bayesian algorithm for robust MEG/EEG source reconstruction.
Cai C, Sekihara K, Nagarajan SS.
Neuroimage. 2018 Jul 27. pii: S1053-8119(18)30671-2. doi: 10.1016/j.neuroimage.2018.07.056.
PDF

Signal space separation method for a biomagnetic sensor array arranged on a flat plane for magnetocardiographic applications: A computer simulation study.
Sekihara K.
J Healthc Eng. 2018 Apr 26;2018:7689589. doi: 10.1155/2018/7689589. eCollection 2018.
https://www.hindawi.com/journals/jhe/2018/7689589/

Beamspace dual signal space projection (bDSSP): a method for selective detection of deep sources in MEG measurements.
Sekihara K, Adachi Y, Kubota HK, Cai C, Nagarajan SS.
J Neural Eng. 2018 Jun;15(3):036026. doi: 10.1088/1741-2552/aab5bd. Epub 2018 Mar 12.
PDF

Subspace-based interference removal methods for a multichannel biomagnetic sensor array.
Sekihara K, Nagarajan SS.
J Neural Eng. 2017 Aug 18;14(5):051001. doi: 10.1088/1741-2552/aa7693.
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Magnetospinography visualizes electrophysiological activity in the cervical spinal cord.
Sumiya S, Kawabata S, Hoshino Y, Adachi Y, Sekihara K, Tomizawa S, Tomori M, Ishii S, Sakaki K, Ukegawa D, Ushio S, Watanabe T, Okawa A.
Sci Rep. 2017 May 19;7(1):2192. doi: 10.1038/s41598-017-02406-8.
https://www.nature.com/articles/s41598-017-02406-8

Recent advancements in the SQUID magnetospinogram system.
Adachi, Y., Kawai, J., Haruta, Y., Miyamoto, M., Kawabata, S., Sekihara, K., & Uehara, G.
Superconductor Science and Technology, 2017, 30(6), 063001.

Dual signal subspace projection (DSSP): a novel algorithm for removing large interference in biomagnetic measurements.
Sekihara K, Kawabata Y, Ushio S, Sumiya S, Kawabata S, Adachi Y,
Nagarajan SS.
J Neural Eng. 2016 Jun;13(3):036007. doi: 10.1088/1741-2560/13/3/036007.
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Development of a Magnetocardiography-based Algorithm for Discrimination between Ventricular Arrhythmias Originating from the Right Ventricular Outflow Tract and the Aortic Sinus Cusp: a Pilot Study.
Ito Y, Shiga K, Yoshida K, Ogata K, Kandori A, Inaba T, Nakazawa Y, Sekiguchi Y, Tada H, Sekihara K, Aonuma K.
Heart Rhythm. 2014 May 30.pii: S1547-5271(14)00618-3.
PDF

Coherent Activity in Bilateral Parieto-Occipital Cortices during P300-BCI Operation.
Takano K, Ora H, Sekihara K, Iwaki S, Kansaku K.
Front Neurol. 2014 May 15;5:74
http://journal.frontiersin.org/Journal/10.3389/fneur.2014.00074/abstract

Complex-value coherence mapping reveals novel abnormal resting-state functional connectivity networks in task-specific focal hand dystonia.
Hinkley LB, Sekihara K, Owen JP, Westlake KP, Byl NN, Nagarajan SS.
Front Neurol. 2013 Oct 10;4:149.
http://journal.frontiersin.org/Journal/10.3389/fneur.2013.00149/full

Disturbed resting functional inter-hemispherical connectivity of the ventral attentional network in alpha band is associated with unilateral spatial neglect.
Sasaki T, Abe M, Okumura E, Okada T, Kondo K, Sekihara K, Ide W, Kamada H.
PLoS One. 2013 Sep 4;8(9):e73416.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762777/

Non-parametric statistical thresholding for sparse magnetoencephalography source reconstructions.
Owen JP, Sekihara K, Nagarajan SS.
Front Neurosci. 2012 Dec 26;6:186.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530032/

Conductive neuromagnetic fields in the lumbar spinal canal.
Ishii S, Kawabata S, Tomizawa S, Tomori M, Sakaki K, Shinomiya K, Sekihara K, Sato T, Adachi Y, Okawa A.
Clin Neurophysiol. 2012 Aug;123(8):1656-61.
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Performance evaluation of the Champagne source reconstruction algorithm on simulated and real M/EEG data.
Owen JP, Wipf DP, Attias HT, Sekihara K, Nagarajan SS.
Neuroimage. 2012 Mar;60(1):305-23.
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Removal of spurious coherence in MEG source-space coherence analysis.
Sekihara K, Owen JP, Trisno S, Nagarajan SS.
IEEE Trans Biomed Eng. 2011 Nov;58(11):3121-9, 2011.
PDF

MEG/EEG Source Reconstruction, Statistical Evaluation, and Visualization with NUTMEG.

Dalal SS, Zumer JM, Guggisberg AG, Trumpis M, Wong DD, Sekihara K, Nagarajan SS.
Comput Intell Neurosci. 2011;2011:758973, 2011 Mar.
http://www.hindawi.com/journals/cin/2011/758973/

A comparison of two-dimensional techniques for converting magnetocardiogram maps into effective current source distributions.
Ogata K, Kandori A, Miyashita T, Sekihara K, Tsukada K.
Rev Sci Instrum. 2011 Jan;82(1):014302.

Array-gain constraint minimum-norm spatial filter with recursively updated gram matrix for biomagnetic source imaging.
Kumihashi I, Sekihara K.
IEEE Trans Biomed Eng. 2010 Jun;57(6):1358-65, 2010.
PDF

Robust Bayesian estimation of the location, orientation, and time course of multiple correlated neural sources using MEG
Wipf DP, Owen JP, Attias HT, Sekihara K, Nagarajan SS.
Neuroimage. 2010 Jan 1;49(1):641-55. Epub 2009 Jul 10.
PDF

Functional imaging of spinal cord electrical activity from its evoked magnetic field
Tomoya Sato, Yoshiaki Adachi, Masaki Tomori, Senichi Ishii, Shigenori Kawabata, Kensuke Sekihara
IEEE Trans Biomed Eng. 2009 Oct;56(10):2452-60.
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Probabilistic algorithms for MEG/EEG source reconstruction using temporal basis functions learned from data.
Zumer JM, Attias HT, Sekihara K, Nagarajan SS.
Neuroimage. 2008;41:924-940.
PDF

Five-dimensional neuroimaging: localization of the time-frequency dynamics of cortical activity.
Dalal SS, Guggisberg AG, Edwards E, Sekihara K, Findlay AM, Canolty RT, Berger MS, Knight RT, Barbaro NM, Kirsch HE, Nagarajan SS.
Neuroimage. 2008 May 1;40(4):1686-700.
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Performance of prewhitening beamforming in MEG dual experimental conditions.
Sekihara K, Hild KE, Dalal SS, Nagarajan SS.
IEEE Trans Biomed Eng. 2008 Mar;55(3):1112-21.
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A probabilistic algorithm integrating source localization and noise suppression for MEG and EEG data.
Zumer JM, Attias HT, Sekihara K, Nagarajan SS.
Neuroimage. 2007 Aug 1;37(1):102-15.
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A probabilistic algorithm for robust interference suppression in bioelectromagnetic sensor data.
Nagarajan SS, Attias HT, Hild KE 2nd, Sekihara K.
Stat Med. 2007 Sep 20;26(21):3886-910.
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Controlled Support MEG imaging.
Nagarajan SS, Portniaguine O, Hwang D, Johnson C, Sekihara K.
Neuroimage. 2006 Sep 13; [Epub ahead of print]
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A novel adaptive beamformer for MEG source reconstruction effective when large background brain activities exist.
Sekihara K, Hild KE 2nd, Nagarajan SS.
IEEE Trans Biomed Eng. 2006 Sep;53(9):1755-64.
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Modified beamformers for coherent source region suppression.
Dalal SS, Sekihara K, Nagarajan SS.
IEEE Trans Biomed Eng. 2006 Jul;53(7):1357-63.
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A graphical model for estimating stimulus-evoked brain responses from magnetoencephalography data with large background brain activity.
Nagarajan SS, Attias HT, Hild KE 2nd, Sekihara K.
Neuroimage. 2006 Apr 1;30(2):400-16. Epub 2005 Dec 19.
PDF

A simple non-parametric statistical thresholding for MEG spatial-filter source reconstruction images.
Sekihara, K., Sahani, M., Nagarajan, S.S.;
NeuroImage, Volume 27, August 2005
Pages: 368-376
PDF

Localization bias and spatial resolution of adaptive and non-adaptive spatial filters for MEG source reconstruction.
Sekihara, K., Sahani, M., Nagarajan, S.S.;
NeuroImage, Volume 25, May 2005
Pages: 1056-1067
PDF

Asymptotic SNR of scalar and vector minimum-variance beamformers for neuromagnetic source reconstruction.
Sekihara, K.; Nagarajan, S.S.; Poeppel, D.; Marantz, A.;
Biomedical Engineering, IEEE Transactions on , Volume: 51 Issue: 10 , Oct 2004
Page(s): 1726-34
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Performance of an MEG adaptive-beamformer source reconstruction technique in the presence of additive low-rank interference.
Sekihara, K.; Nagarajan, S.S.; Poeppel, D.; Marantz, A.;
Biomedical Engineering, IEEE Transactions on , Volume: 51 Issue: 1 , Jan 2004
Page(s): 90-99
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NUTMEG: a neuromagnetic source reconstruction toolbox.
Dalal SS, Zumer JM, Agrawal V, Hild KE, Sekihara K, Nagarajan SS.
Neurol Clin Neurophysiol. 2004 Nov 30;2004:52.
PDF

Muscle afferent inputs from the hand activate human cerebellum sequentially through parallel and climbing fiber systems.
Hashimoto I., Kimura. T, Tanosaki M., Iguchi Y., Sekihara K.
Clin Neurophysiol. 2003 Nov;114(11)
Pages:2107-17.
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Modulation of auditory cortex during speech: An MEG study
J. Houde, S. S. Nagarajan, K. Sekihara, M. Merzenich
Journal of Cognitive Neuroscience, Vol.14(8), 2002
Pages: 1125-1138
PDF

Performance of an MEG adaptive-beamformer technique in the presence of correlated neural activities: effects on signal intensity and time-course estimates
Sekihara, K.; Nagarajan, S.S.; Poeppel, D.; Marantz, A.;
Biomedical Engineering, IEEE Transactions on , Volume: 49 Issue: 12 , Dec 2002
Page(s): 1534 -1546
PDF

Application of an MEG eigenspace beamformer to reconstructing spatio-temporal activities of neural sources
K. Sekihara, S. S. Nagarajan, D. Poeppel, A. Marantz, Y. Miyashita
Human Brain Mapping, Vol. 15, 2002
Pages: 199-215
PDF

Temporal characrerization of memory retrieval processes: an fMRI study of the 'tip of the tongue' phenomenon
H. Kikyo, K. Ohki, K. Sekihara,
European Journal of Neuroscience, Vol.14, 2001.
Pages: 887-892
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Serial activation of distinct cytoarchitectonic areas of the human SI cortex after posterior tibial nerve stimulation
I. Hashimoto, K. Sakuma, T. Kimura, Y. Iguchi, K. Sekihara
NeuroReport, Vol. 12, 2001
Pages: 1857-1862
PDF

Dynamic activation of distinct cytoarchitectonic areas of the human SI cortex after median nerve stimulation
I. Hashimoto, T. Kimura, Y. Iguchi, R. Takino, K. Sekihara
NeuroReport, Vol. 12, 2001
Pages: 1891-1897
PDF

Reconstructing spatio-temporal activities of neural sources using an MEG vector beamformer technique
Sekihara, K.; Nagarajan, S.S.; Poeppel, D.; Marantz, A.; Miyashita, Y.;
Biomedical Engineering, IEEE Transactions on , Volume: 48 Issue: 7 , Jul 2001
Page(s): 760 -771
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Neural source estimation from a time-frequency component of somatic evoked high-frequency magnetic oscillations to posterior tibial nerve stimulation
K. Sakuma, K. Sekihara, and I. Hashimoto
Electroencephalography and Clinical Neurophysiology, Vol.110, 1999
Pages: 1585-1588
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Estimating neural sources from each time-frequency component of magnetoencephalographic data
Sekihara, K.; Nagarajan, S.S.; Poeppel, D.; Miyauchi, S.; Fujimaki, N.; Koizumi, H.; Miyashita, Y.;
Biomedical Engineering, IEEE Transactions on , Volume: 47 Issue: 5 , May 2000
Page(s): 642 -653
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Time-frequency MEG-MUSIC algorithm
Sekihara, K.; Nagarajan, S.; Poeppel, D.; Miyashita, Y.;
Medical Imaging, IEEE Transactions on , Volume: 18 Issue: 1 , Jan 1999
Page(s): 92 -97
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MEG spatio-temporal analysis using a covariance matrix calculated from nonaveraged multiple-epoch data
Sekihara, K.; Poeppel, D.; Marantz, A.; Koizumi, H.; Miyashita, Y.;
Biomedical Engineering, IEEE Transactions on , Volume: 46 Issue: 5 , May 1999
Page(s): 515 -521
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Activation of lateral extrastriate areas during orthographic processing of Japanese characters studied with fMRI
I. Uchida H. Kikyo K. Nakajima S. Konishi K. Sekihara Y. Miyashita
Neuroimage,Vol.9, 1999
Pages: 208-215

Comparison of covariance-based and waveform-based subtraction methods in removing the interference from button-pressing finger movements
K. Sekihara D. Poeppel, A. Marantz, H. Koizumi, Y. Miyashita
Brain Topography, Vol.11, 1998
Pages: 95-102
PDF is available upon request.

Transient activation of inferior prefrontal cortex during cognitive set shifting
S. Konishi, K. Nakajima, I. Uchida, M. Kameyama, K. Nakahara, K. Sekihara, Y. Miyashita,
Nature neuroscience, Vol.1, 1998
Pages: 80-84

No-go dominant brain activity in human inferior prefrontal cortex revealed by functional magnetic resonance imaging
S. Konishi, K. Nakajima, I. Uchida, K. Sekihara Y. Miyashita
European Journal of Neuroscience, Vol.10, 1998
Pages: 1209-1213

MEG covariance difference analysis: a method to extract target source activities by using task and control measurements
Sekihara, K.; Poeppel, D.; Marantz, A.; Phillips, C.; Koizumi, H.; Miyashita, Y.;
Biomedical Engineering, IEEE Transactions on , Volume: 45 Issue: 1 , Jan 1998
Page(s): 87 -97
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Noise covariance incorporated MEG-MUSIC algorithm: a method for multiple-dipole estimation tolerant of the influence of background brain activity
Sekihara, K.; Poeppel, D.; Marantz, A.; Koizumi, H.; Miyashita, Y.;
Biomedical Engineering, IEEE Transactions on , Volume: 44 Issue: 9 , Sep 1997
Page(s): 839 -847
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Detecting cortical activities from fMRI time-course data using the MUSIC algorithm with forward and backward covariance averaging
K. Sekihara and H. Koizumi
Magnetic Resonance in Medicine, Vol.35, 1996
Pages: 807-813

Reconstruction of two-dimensional current distribution from tangential MCG measurement
A. Kandori, K. Tsukata, Y. Haruta, Y. Noda, Y. Terada, T. Mitsui, K. Sekihara
Physics in Medicine and Biology, Vol.41, 1996
Pages: 1705-1716

Generalized Wiener estimation of three-dimensional current distribution from biomagnetic measurements
Sekihara, K.; Scholz, B.;
Biomedical Engineering, IEEE Transactions on , Volume: 43 Issue: 3 , Mar 1996
Page(s): 281 -291
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Suppression of background brain activity influence in localizing epileptic spike source from biomagnetic measurement
K. Sekihara, K. Abraham-Fuchs, H. Stefan, E. Hellstrand
Brain Topography, Vol.8, 1996
Pages: 323-328

Estimation of electrical source localization using the temporal correlation between magnetic field measurements
T. Obi, N. Ohyama, M. Yamaguchi, K. Sekihara
Optical Review, Vol.2, 1995
Pages: 115-119

Average-intensity reconstruction and Wiener reconstruction of bioelectric current distribution based on its estimated covariance matrix
Sekihara, K.; Scholz, B.;
Biomedical Engineering, IEEE Transactions on , Volume: 42 Issue: 2 , Feb 1995
Page(s): 149 -157
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Reconstructing current distributions from biomagnetic measurements under large external noise disturbances
Sekihara, K.; Scholz, B.; Bruder, H.;
Medical Imaging, IEEE Transactions on , Volume: 13 Issue: 1 , Mar 1994
Page(s): 144 -151
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Reduction of brain noise influence in evoked neuromagnetic source localization using noise spatial correlation
K. Sekihara, F. Takeuchi, S. Kuriki, and H. Koizumi
Physics in Medicine and Biology, Vol.39, 1994
Pages: 937-946

Multiple current dipole estimation using simulated annealing
Haneishi, H.; Ohyama, N.; Sekihara, K.; Honda, T.;
Biomedical Engineering, IEEE Transactions on , Volume: 41 Issue: 11 , Nov 1994
Page(s): 1004 -1009

Relationship between dipole parameter estimation errors and measurement conditions in magnetoencephalography
Ogura, Y.; Sekihara, K.;
Biomedical Engineering, IEEE Transactions on , Volume: 40 Issue: 9 , Sep 1993
Page(s): 919 -924

Details of simulated annealing algorithm to estimate parameters of multiple current dipoles using biomagnetic data
Sekihara, K.; Haneishi, H.; Ohyama, N.;
Medical Imaging, IEEE Transactions on , Volume: 11 Issue: 2 , Jun 1992
Page(s): 293 -299

Maximum-likelihood estimation of current-dipole parameters for data obtained using multichannel magnetometer
Sekihara, K.; Ogura, Y.; Hotta, M.;
Biomedical Engineering, IEEE Transactions on , Volume: 39 Issue: 6 , Jun 1992
Page(s): 558 -562

↑Pagetop

Kensuke Sekihara, Ph D

Founder & CEO
Signal Analysis Inc.

Research Professor
Department of Advanced Technology in Medicine,
Tokyo Medical & Dental University

Professor Emeritus
Tokyo Metropolitan University

fellow IEEE
fellow ISFSI (International Society for
FunctionalSource Imaging)

E-mail:k-sekihara*at*nifty.com